Abstract | BACKGROUND/AIMS: METHODS: Among 22 patients with AFLP, 16 cases were treated with conventional treatment (CT group), while the other 6 cases were treated with PE and PP in addition to conventional therapy (CT+PE+PP group). Treatment efficacy was based primarily on survival and secondarily on liver and kidney functions 2 weeks after treatment. Adverse effects were also assessed at the same time point. RESULTS: In the CT+PE+PP group, 5 (83.3%) patients improved, while 1 (16.7%) patient died of multiple organ dysfunction syndrome. In the CT group, 3 (18.75%) patients improved, while 13 (81.2%) patients died of complications. Liver and kidney functions and survival were significantly improved in the CT+PE+PP group (p < 0.05) compared to the CT group. CONCLUSIONS: Timely application of PE and PP in the early phase of AFLP may be a promising treatment to halt or reverse the progression of AFLP.
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Authors | Juan Ding, Li-Ping Han, Xiao-Ping Lou, Li-Na Geng, Dong Liu, Qin Yang, Shan Gao |
Journal | Gynecologic and obstetric investigation
(Gynecol Obstet Invest)
Vol. 79
Issue 2
Pg. 97-100
( 2015)
ISSN: 1423-002X [Electronic] Switzerland |
PMID | 25634306
(Publication Type: Journal Article)
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Copyright | © 2015 S. Karger AG, Basel. |
Topics |
- Adult
- Combined Modality Therapy
- Fatty Liver
(therapy)
- Female
- Hemoperfusion
(methods)
- Humans
- Plasma Exchange
(methods)
- Pregnancy
- Pregnancy Complications
(therapy)
- Retrospective Studies
- Treatment Outcome
- Young Adult
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