Abstract | OBJECTIVE: To determine the prevalence and type of ultrasonographic (US) lesions of the anterior chest wall (ACW) in cases of spondyloarthritis (SpA). METHODS: This monocentric, prospective, and controlled study included patients consulting for SpA (Assessment of Spondyloarthritis International Society criteria) and control subjects. Clinical ( pain and swelling) and US assessments ( synovitis, joint effusion, erosion, ankylosis, margin narrowing, or Doppler signal) were performed on the sternoclavicular (SCJ) and the manubriosternal (MSJ) joints. The main characteristics of SpA were recorded [disease duration, biologic features, Ankylosing Spondylitis Disease Activity Score (ASDAS), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), radiographic and extraarticular involvement]. RESULTS: The study included 131 patients with SpA and 49 control subjects (same age and sex ratio). Clinical and US involvement of ACW were found in, respectively, 39% and 35.5% of SpA and in 12% and 14.3% of controls (p < 0.01). US highlighted erosions (34 vs 0), margin narrowing (12 vs 0), power Doppler activity (18 vs 2; p < 0.05), and ankylosis of the MSJ (24 vs 3). US involvement was associated with disease duration (14.9 vs 11.1 years; p = 0.04), age (45 vs 41 years; p = 0.004), radiographic change of sacroiliac joint (p = 0.05), and presence of inflammatory bowel disease (IBD; p = 0.03). No associations were found with HLA-B27, psoriasis, enthesitis, uveitis, or clinical involvement of ACW. Clinical involvement is associated with a higher BASDAI (47 vs 32; p = 0.0009) and ASDAS (2.9 vs 2.2; p = 0.006). CONCLUSION: US involvement of ACW is frequent in SpA (36.5%), mainly with erosion of SCJ and ankylosis of MSJ. It is associated with disease duration, radiographic sacroiliitis, and IBD.
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Authors | Frank Verhoeven, Xavier Guillot, Marie Godfrin-Valnet, Clément Prati, Daniel Wendling |
Journal | The Journal of rheumatology
(J Rheumatol)
Vol. 42
Issue 1
Pg. 87-92
(Jan 2015)
ISSN: 0315-162X [Print] Canada |
PMID | 25362653
(Publication Type: Journal Article)
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Topics |
- Adult
- Female
- Humans
- Male
- Middle Aged
- Prospective Studies
- Severity of Illness Index
- Spondylarthritis
(diagnostic imaging)
- Synovitis
(diagnostic imaging)
- Thoracic Wall
(diagnostic imaging)
- Ultrasonography
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