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CEA a thrombus CAM: CEACAM2, a twin of CEACAM1?

Abstract
In this issue of Blood, Alshahrani et al demonstrate that carcinoembryonic antigen-related cell adhesion molecule 2 (CEACAM2) is expressed on platelets and negatively regulates the collagen receptor glycoprotein (GP)VI-FcRγ chain and C-type lectin-like receptor 2 (CLEC-2)-mediated platelet activation.
AuthorsAndrea Kristina Horst
JournalBlood (Blood) Vol. 124 Issue 15 Pg. 2323-4 (Oct 09 2014) ISSN: 1528-0020 [Electronic] United States
PMID25301335 (Publication Type: Journal Article, Comment)
Chemical References
  • Antigens, CD
  • CD66 antigens
  • CLEC-2 protein, mouse
  • Cell Adhesion Molecules
  • Lectins, C-Type
  • Platelet Membrane Glycoproteins
  • platelet membrane glycoprotein VI
Topics
  • Animals
  • Antigens, CD (metabolism)
  • Cell Adhesion Molecules (metabolism)
  • Lectins, C-Type (metabolism)
  • Platelet Membrane Glycoproteins (metabolism)
  • Signal Transduction
  • Thrombosis (metabolism, pathology)

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