Successful in utero intervention for bilateral renal agenesis.

Abstract

BACKGROUND:

We report a case of bilateral renal agenesis treated with serial amnioinfusion in which the newborn survived the newborn period and was able to undergo peritoneal dialysis as a bridge to planned renal transplantation.

CASE:

A 34-year-old woman, gravida 1 para 0, presented at 23 1/7 weeks of gestation with a diagnosis of anhydramnios and bilateral renal agenesis. The patient underwent weekly serial amnioinfusion with the goal of improving fetal pulmonary development. At 28 weeks of gestation, the patient delivered a live newborn who required minimal respiratory support. The neonate is currently 9 months old and is undergoing daily peritoneal dialysis.

CONCLUSION:

Serial amnioinfusion appears to have mitigated the severe pulmonary compromise that has, in the past, led to the death of newborns with bilateral renal agenesis.

• Authors: Jessica L Bienstock, Meredith L Birsner, Fred Coleman, Nancy A Hueppchen
• Journal: Obstetrics and gynecology (Obstet Gynecol) Vol. 124 Issue 2 Pt 2 Suppl 1 Pg. 413-415 (Aug 2014) ISSN: 1873-233X [Electronic] United States
• PMID: 25004316 (Publication Type: Case Reports, Journal Article)

Topics

• Abnormalities, Multiple (etiology, prevention & control)
• Adult
• Congenital Abnormalities (therapy)
• Female
• Fetal Diseases (therapy)
• Fetal Therapies
• Humans
• Infant, Newborn
• Kidney (abnormalities)
• Kidney Diseases (complications, congenital, therapy)
• Lung (abnormalities)
• Lung Diseases (etiology, prevention & control)
• Peritoneal Dialysis
• Pregnancy