[PVB therapy for advanced testicular cancer].

Abstract

Twelve cases of advanced testicular cancer, including 5 cases of seminoma, 3 cases of teratocarcinoma, 1 case of yolk sac tumor, 1 case of embryonal carcinoma and 2 cases of mixed cell type, were treated with cisplatin-vinblastine-bleomycin (PVB) therapy. Among them, 10 cases had measurable metastatic lesions and the objective response rate was 80%. Three cases showed complete response. Ten cases showed nonexistent disease after PVB therapy and salvage operation. Though PVB therapy was useful for the treatment of advanced testicular cancer, a few cases having poor prognostic factors showed no response to the therapy.

• Authors: M Nakao, S Nakagawa, K Toyoda, M Nukui, H Takada, K Ebisui, K Sugimoto, H Watanabe, M Maegawa, K Miyakoda
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 35 Issue 11 Pg. 1871-5 (Nov 1989) ISSN: 0018-1994 [Print] Japan
• PMID: 2482672 (Publication Type: English Abstract, Journal Article)

Chemical References

• Bleomycin
• Vinblastine
• Cisplatin

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Bleomycin (administration & dosage)
• Cisplatin (administration & dosage)
• Dysgerminoma (drug therapy)
• Humans
• Male
• Mesonephroma (drug therapy)
• Middle Aged
• Neoplasms, Germ Cell and Embryonal (drug therapy)
• Teratoma (drug therapy)
• Testicular Neoplasms (drug therapy)
• Vinblastine (administration & dosage)