In vivo biocompatibility versus degree of conversion of resin-reinforced cements in different time periods.

Abstract

This study focused on test the null hypothesis that there is no difference between the degree of conversion and biocompatibility of different resin reinforced glass ionomer cements (RRGICs). Forty-eight male Wistar rats were used, distributed into four groups (n = 12), as follows: Group C (Control, polyethylene), Group FOB (Fuji Ortho Band), Group UBL (Ultra band Lok), and Group MCG (Multicure Glass), in subcutaneous tissue. The events of edema, necrosis, granulation tissue, multinuclear giant cells, young fibroblasts, and collagen formation were analyzed at 7, 15, and 30 days. The degree of conversion was evaluated by the Fourier method. Biocompatibility and degree of conversion were assessed using the Kruskal-Wallis and Dunn tests, and ANOVA and Tukey's test, respectively (P < 0.05). It was observed that, there was significant difference between Groups FOB and UBL for the presence of young fibroblasts at 15 days (P = 0.034) and between the Control and MCG Groups for the presence of multinucleated giant cells at 30 days (P = 0.009). Monomer conversion increased progressively until day 30, with significant difference between Group FOB and Groups UBL and MCG (P = 0.013) at 15 days. The null hypothesis was partially accepted, Fuji Ortho Band showed a less monomer conversion and a smaller number of young fibroblasts in the time of 15 days.

• Authors: Rogério Lacerda-Santos, Maria Isabel Serpa Simões De Farias, Fabiola Galbiatti De Carvalho, Matheus Melo Pithon, Pollianna Muniz Alves, Orlando Motohiro Tanaka, Gymenna Maria Tenório Guênes
• Journal: Microscopy research and technique (Microsc Res Tech) Vol. 77 Issue 5 Pg. 335-40 (May 2014) ISSN: 1097-0029 [Electronic] United States
• PMID: 24615757 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2014 Wiley Periodicals, Inc.

Chemical References

• Acrylic Resins
• Aluminum Silicates
• Fuji Ortho
• Glass Ionomer Cements
• Resin Cements
• Ultra Band-Lok

Topics

• Acrylic Resins (adverse effects, metabolism)
• Aluminum Silicates (adverse effects, metabolism)
• Animals
• Edema (chemically induced)
• Fibroblasts (metabolism)
• Giant Cells (metabolism)
• Glass Ionomer Cements (adverse effects, metabolism)
• Inflammation (chemically induced)
• Male
• Materials Testing (methods)
• Necrosis (chemically induced)
• Rats, Wistar
• Resin Cements (adverse effects, metabolism)
• Time Factors