Abstract | BACKGROUND: OBJECTIVE: To determine whether surface fragmented ECG (fQRS) helps identifying patients with CChC and ICDs at higher risk of presenting appropriate ICD therapies. METHODS: Multicenter retrospective study. All patients with CChC and ICDs were analyzed. Clinical demographics, surface ECG, and ICD therapies were collected. RESULTS: A total of 98 patients were analyzed. Another four cases were excluded due to pacing dependency. Mean age was 55.5 ± 10.4 years, male gender 65%, heart failure New York Heart Association class I 47% and II 38%. Mean left ventricular ejection fraction (LVEF) 39.6 ± 11.8%. The indication for ICD was secondary prevention in 70% of patients. fQRS was found in 56 patients (59.6%). Location of fragmentation was inferior (57.1%), lateral (35.7%), and anterior (44.6%). Rsr pattern was the more prevalent (57.1%). Predictors of appropriate therapy in the multivariate model were: increased age (P = 0.01), secondary prevention indication (P = 0.01), ventricular pacing >50% of the time (P = 0.004), and LVEF <30% (P = 0.01). The presence of fQRS did not identify patients at higher risk of presenting appropriate therapies delivered by the ICD (P = 0.87); regardless of QRS interval duration. CONCLUSIONS: fQRS is highly prevalent among patients with CChC. It has been found a poor predictor of appropriate therapies delivered by the ICD in this population.
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Authors | Adrian Baranchuk, Francisco Femenia, Juan Cruz López-Diez, Claudio Muratore, Mariana Valentino, Enrique Retyk, Nestor Galizio, Darío Di Toro, Karina Alonso, Wilma M Hopman, Rodrigo Miranda, FECHA Study Investigators |
Journal | Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
(Ann Noninvasive Electrocardiol)
Vol. 19
Issue 1
Pg. 43-9
(Jan 2014)
ISSN: 1542-474X [Electronic] United States |
PMID | 24460805
(Publication Type: Journal Article, Multicenter Study)
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Copyright | ©2013 Wiley Periodicals, Inc. |
Topics |
- Arrhythmias, Cardiac
(complications, diagnosis)
- Brugada Syndrome
- Cardiac Conduction System Disease
- Chagas Cardiomyopathy
(complications, surgery)
- Death, Sudden, Cardiac
(prevention & control)
- Defibrillators, Implantable
- Electrocardiography
(methods, statistics & numerical data)
- Female
- Heart Conduction System
(abnormalities)
- Humans
- Male
- Middle Aged
- Retrospective Studies
- Risk Factors
- Treatment Outcome
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