Abstract | OBJECTIVE: Aim of this study is to evaluate the efficacy of a phytotherapic which includes Solidago, Orthosiphon and Birch extract (Cistimev®) in association with antibiotic prophylaxis in female patients affected by recurrent urinary tract infections (UTIr). MATERIALS AND METHODS: RESULTS: 164 consecutive patients were studied: 107 were included in group A (mean age 59 ± 17.3 years) and 57 (mean age 61 ± 15.7) in group B. During the treatment period the relapse frequencies between the two groups were not significantly different (p = 0.854): 12/107 (11.21%) patients interrupted the treatment for UTIr in group A and 6/57 (10.52%) in group B. In the long term follow-up the relapse UTI risk was significant different in the two groups with a relapse risk 2.5 greater in group B than in group A (p < 0.0001). CONCLUSION: Our study demonstrated that in female patients affected by recurrent UTI, the association between antibiotic prophylaxis and of a phytotherapic which includes Solidago, Orthosiphon and Birch extract reduced the number of UTI in the 12 months following the end of prophylaxis and obtained a longer relapsing time, greatly improving the quality of life of the patients.
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Authors | Emanuela Frumenzio, Daniele Maglia, Eleonora Salvini, Silvia Giovannozzi, Manuel Di Biase, Vittorio Bini, Elisabetta Costantini |
Journal | Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
(Arch Ital Urol Androl)
Vol. 85
Issue 4
Pg. 197-9
(Dec 31 2013)
ISSN: 1124-3562 [Print] Italy |
PMID | 24399121
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Dioxolanes
- Fluoroquinolones
- Piperazines
- Fosfomycin
- prulifloxacin
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Topics |
- Anti-Bacterial Agents
(therapeutic use)
- Antibiotic Prophylaxis
- Combined Modality Therapy
- Dioxolanes
(therapeutic use)
- Female
- Fluoroquinolones
(therapeutic use)
- Fosfomycin
(therapeutic use)
- Humans
- Middle Aged
- Phytotherapy
- Piperazines
(therapeutic use)
- Recurrence
- Retrospective Studies
- Urinary Tract Infections
(prevention & control)
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