Abstract | INTRODUCTION: Despite new treatment options targeted at its three main pathogenic pathways, prognosis of idiopathic pulmonary arterial hypertension has remained dismal, with 3-year survival rates around 70 %. Antiproliferative agents have emerged as a new therapeutic concept. However, they may exert their effects only after a prolonged period of time. CASE DESCRIPTION: CONCLUSIONS:
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Authors | Rudolf Speich, Ursula Treder, Guido Domenighetti, Lars C Huber, Silvia Ulrich |
Journal | International journal of clinical pharmacy
(Int J Clin Pharm)
Vol. 36
Issue 2
Pg. 256-60
(Apr 2014)
ISSN: 2210-7711 [Electronic] Netherlands |
PMID | 24287663
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Benzamides
- Piperazines
- Prostaglandins
- Protein Kinase Inhibitors
- Pyrimidines
- Imatinib Mesylate
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Topics |
- Adult
- Benzamides
(therapeutic use)
- Familial Primary Pulmonary Hypertension
(drug therapy, physiopathology)
- Female
- Hemodynamics
(drug effects)
- Humans
- Imatinib Mesylate
- Injections, Intravenous
- Piperazines
(therapeutic use)
- Prostaglandins
(therapeutic use)
- Protein Kinase Inhibitors
(therapeutic use)
- Pyrimidines
(therapeutic use)
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