[Clinical observation of influence of warfarin on post-operative bleeding after tooth extraction in the elderly].

Abstract

OBJECTIVE:

To investigate the feasibility of continuing warfarin when international normalized ratio (INR) was less than 2.5 before tooth extraction in the elderly.

METHODS:

One hundred elderly outpatients with prolong use of warfarin and maintaining INR < 2.5 before tooth extraction served as observation group, 200 elderly outpatients without taking anticoagulant and antiplatelet medicine served as control group. All the patients underwent a single non-impacted tooth extraction. Postoperative bleeding at different time was observed.

RESULTS:

There was significant difference in postoperative bleeding at 5, 10, 30 min, 24 h after extraction and there was no significant difference at 48 h between control group and observation group (P < 0.05) and no bleeding was found in either group at 48 h (incidence of bleeding were 0%).

CONCLUSIONS:

It was feasible to continue warfarin for the elderly maintaining INR < 2.5 undergoing a single non-impacted tooth extraction by monitoring postoperative bleeding and hemostatic treatment measures.

• Authors: Wen-ying Wang, Nian-hui Cui, En-bo Wang, Wei Zhang
• Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology (Zhonghua Kou Qiang Yi Xue Za Zhi) Vol. 48 Issue 7 Pg. 385-7 (Jul 2013) ISSN: 1002-0098 [Print] China
• PMID: 24262040 (Publication Type: Controlled Clinical Trial, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anticoagulants
• Warfarin

Topics

• Age Factors
• Aged
• Aged, 80 and over
• Anticoagulants (administration & dosage, adverse effects)
• Female
• Humans
• International Normalized Ratio
• Male
• Middle Aged
• Postoperative Hemorrhage (etiology)
• Tooth Extraction (adverse effects)
• Warfarin (administration & dosage, adverse effects)