Abstract | BACKGROUND: OBJECTIVES: MATERIALS AND METHODS: Overnight fasted male Wistar rats (150-200 g) were randomly divided into normal control group [4% Dimethyl Sulfoxide ( DMSO), i.p.], positive control group ( Triton WR-1339 in 4% DMSO, 400 mg/kg, i.p.), standard drug treated ( fenofibrate 65 mg/kg, p.o. for 7 days after inducing hyperlipidemia) and Arogyavardhini vati treated (50, 100, 200 mg/kg, p.o. for 7 days after inducing hyperlipidemia). Rat doses were calculated by extrapolating the equivalent human dose (therapeutic dose, sub-maximum, and maximum dose). Serum total cholesterol, triglyceride, low-density lipoprotein ( LDL), high-density lipoprotein HDL, liver malondialdehyde (MDA), and glutathione (GSH) levels were estimated at end of experiments. RESULTS: CONCLUSION:
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Authors | Gajendra Kumar, Amita Srivastava, Surinder Kumar Sharma, Yogendra Kumar Gupta |
Journal | Journal of Ayurveda and integrative medicine
(J Ayurveda Integr Med)
Vol. 4
Issue 3
Pg. 165-70
(Jul 2013)
ISSN: 0975-9476 [Print] United States |
PMID | 24250146
(Publication Type: Journal Article)
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