Whipple's disease in an HLA-B27 positive female.

Abstract

The first reported case of Whipple's disease in a female who was HLA-B27 positive and had asymptomatic sacroiliitis is discussed. She presented great difficulty in diagnosis as she had multi-system involvement without diarrhea. This case supports the hypothesis that Whipple's disease is a disorder related to HLA-B27.

• Authors: R McKinley, C S Grace
• Journal: Australian and New Zealand journal of medicine (Aust N Z J Med) Vol. 15 Issue 6 Pg. 758-60 (Dec 1985) ISSN: 0004-8291 [Print] Australia
• PMID: 2423065 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Infective Agents
• Drug Combinations
• HLA Antigens
• HLA-B27 Antigen
• Chloramphenicol
• Trimethoprim, Sulfamethoxazole Drug Combination
• Trimethoprim
• Sulfamethoxazole

Topics

• Anti-Infective Agents (therapeutic use)
• Arthritis (complications)
• Biopsy
• Chloramphenicol (therapeutic use)
• Drug Combinations (therapeutic use)
• Female
• HLA Antigens (analysis)
• HLA-B27 Antigen
• Humans
• Intestine, Small (pathology)
• Lymph Nodes (ultrastructure)
• Lymphadenitis (complications)
• Middle Aged
• Radiography
• Sacroiliac Joint (diagnostic imaging)
• Sex Factors
• Sulfamethoxazole (therapeutic use)
• Trimethoprim (therapeutic use)
• Trimethoprim, Sulfamethoxazole Drug Combination
• Whipple Disease (complications, drug therapy, immunology, pathology)