Abstract | BACKGROUND & AIMS: METHODS: We performed a cross-sectional study that analyzed data from 539 individuals with diverticulosis and 1569 without (controls). Participants underwent colonoscopy and assessment of diet, physical activity, and bowel habits. Our analysis was limited to participants with no knowledge of their diverticular disease to reduce the risk of biased responses. RESULTS:
Constipation was not associated with an increased risk of diverticulosis. Participants with less frequent bowel movements (<7/wk) had reduced odds of diverticulosis compared with those with regular bowel movements (7/wk) (odds ratio [OR], 0.56; 95% confidence interval [CI], 0.40-0.80). Those reporting hard stools also had reduced odds (OR, 0.75; 95% CI, 0.55-1.02). There was no association between diverticulosis and straining (OR, 0.85; 95% CI, 0.59-1.22) or incomplete bowel movement (OR, 0.85; 95% CI, 0.61-1.20). We found no association between dietary fiber intake and diverticulosis (OR, 0.96; 95% CI, 0.71-1.30) in comparing the highest quartile with the lowest (mean intake, 25 vs 8 g/day). CONCLUSIONS: In our cross-sectional, colonoscopy-based study, neither constipation nor a low-fiber diet was associated with an increased risk of diverticulosis.
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Authors | Anne F Peery, Robert S Sandler, Dennis J Ahnen, Joseph A Galanko, Adrian N Holm, Aasma Shaukat, Leila A Mott, Elizabeth L Barry, David A Fried, John A Baron |
Journal | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
(Clin Gastroenterol Hepatol)
Vol. 11
Issue 12
Pg. 1622-7
(Dec 2013)
ISSN: 1542-7714 [Electronic] United States |
PMID | 23891924
(Publication Type: Journal Article, Research Support, N.I.H., Extramural)
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Copyright | Copyright © 2013 AGA Institute. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adult
- Aged
- Colonoscopy
- Constipation
(complications)
- Cross-Sectional Studies
- Dietary Fiber
(administration & dosage)
- Diverticulum
(epidemiology)
- Feeding Behavior
- Female
- Humans
- Male
- Middle Aged
- Motor Activity
- Risk Assessment
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