Abstract | BACKGROUND: METHOD: We conducted a pair-wise, case-control study with 1:1 matching, reviewing records over a 13-year period (1990-2002) for the intensive care unit (ICU) of the Habib Bourguiba University Hospital, Sfax, Tunisia. A total of 184 children were included in the study (92 cases and 92 controls); cases received hydrocortisone hemisuccinate during hospitalization and controls received no steroids. Patients were matched according to age (±2 years), severity factors at admission ( pulmonary edema and grades of severity of scorpion envenomation) and scorpion antivenom administration. RESULTS: Cases and controls did not differ significantly in age (4.9 ± 5.5 years vs 6.2 ± 3.8 years; p > 0.05), mean temperature on admission (37.2 ± 1.2 vs 37.2 ± 1.06; p = 0.99) or presence of systemic inflammatory response syndrome (SIRS) (77 vs 70; p = 0.198). The proportion of patients with pulmonary edema was similar in the two groups (77 vs 71; p > 0.05), and in each group 46 patients (50%) received scorpion antivenom (p > 0.05). The use of mechanical ventilation, ICU length of stay and ICU mortality was not significantly different between the studied groups. CONCLUSION:
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Authors | Mabrouk Bahloul, Anis Chaari, Rania Ammar, Rania Allala, Hassen Dammak, Olfa Turki, Hedi Chelly, Chokri Ben Hamida, Mounir Bouaziz |
Journal | Transactions of the Royal Society of Tropical Medicine and Hygiene
(Trans R Soc Trop Med Hyg)
Vol. 107
Issue 6
Pg. 349-55
(Jun 2013)
ISSN: 1878-3503 [Electronic] England |
PMID | 23610162
(Publication Type: Journal Article)
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Chemical References |
- Anti-Inflammatory Agents
- Antivenins
- Scorpion Venoms
- hydrocortisone hemisuccinate
- Hydrocortisone
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Topics |
- Anti-Inflammatory Agents
(therapeutic use)
- Antivenins
(therapeutic use)
- Bites and Stings
(complications, drug therapy, mortality)
- Case-Control Studies
- Child
- Child, Preschool
- Female
- Humans
- Hydrocortisone
(analogs & derivatives, therapeutic use)
- Infant
- Inflammation
(drug therapy, etiology)
- Length of Stay
- Male
- Scorpion Venoms
(poisoning)
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