Abstract | AIM: METHODS: We performed an interventional study in patients after successful resuscitation from cardiac arrest admitted to the emergency department of a tertiary care centre. The extracorporeal veno-venous circulation was established via a percutaneously introduced double lumen dialysis catheter in the femoral vein, and a tubing circuit and heat exchanger. A paediatric cardiopulmonary bypass roller pump and a heater-cooler system were used to circulate the blood. Main outcome measures were feasibility, efficacy, and safety. RESULTS: We included eight consecutive cardiac arrest patients with a median oesophageal temperature of 35.9°C (interquartile range 34.9-37.0). A median time of 8 min elapsed (interquartile range 5-15 min) to reach oesophageal temperatures below 34°C, which reflects a cooling rate of 12.2°C/h (interquartile range 10.8°C/h to 14.1°C/h). The predefined target temperature of 33.0°C was reached after 14 min (interquartile range 8-21 min). No device or method related adverse events were reported. CONCLUSION: Extracorporeal veno-venous blood cooling is a feasible, safe, and very fast approach for induction of mild therapeutic hypothermia in patients successfully resuscitated from cardiac arrest.
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Authors | Christoph Testori, Michael Holzer, Fritz Sterz, Peter Stratil, Zeno Hartner, Francesco Moscato, Heinrich Schima, Wilhelm Behringer |
Journal | Resuscitation
(Resuscitation)
Vol. 84
Issue 8
Pg. 1051-5
(Aug 2013)
ISSN: 1873-1570 [Electronic] Ireland |
PMID | 23537698
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2013 Elsevier Ireland Ltd. All rights reserved. |
Topics |
- Aged
- Austria
- Body Temperature
- Equipment Design
- Extracorporeal Circulation
(instrumentation, methods)
- Feasibility Studies
- Female
- Humans
- Hypothermia, Induced
(methods)
- Male
- Middle Aged
- Monitoring, Physiologic
- Out-of-Hospital Cardiac Arrest
(physiopathology, therapy)
- Outcome and Process Assessment, Health Care
- Prospective Studies
- Resuscitation
(methods)
- Survival Rate
- Time Factors
- Treatment Outcome
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