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[Duodenal polyps: epidemiology, clinical picture, diagnostics].

Abstract
This cross-sectional comparative study included 120 patients (68 men and 52 women, mean age 58.3 +/- 14.5 yr) with duodenal polyps (DP) diagnosed by fibroesophagogastroduodenoscopy. Morphological study was conducted in 118 patients. Gastric metaplasia (GM) areas in polyp mucosa (PM) were identified by alcian blue/PAS reaction at pH 1.0 and 2.5. A total of 82859 patients were examined. Endoscopy revealed DP in 0.15% of them. The pH value below 6.5 was documented in duodenal bulb polyps in 85% of the patients having them and in 20% of those with polyps of other localization. Biliary pathology was documented in 80% of the patient with DP in major duodenal papilla and in 2.0% of those with DP of different localization. 66.7% of the patients did not complain of pain in the upper part of the gastrointestinal tract. Erosion of polyp mucosa occurred in 21.2% of the patients (92% of erosions in duodenal bulbs and 56.5% in hyperplastic DP with GM areas). H. pylori was identified in GM areas of bulb DP in 30.4% of the patients. Endoscopic study of 120 patients revealed the following localization of DP: bulbs - 83.4%, postbulbar region - 8.3%, major duodenal papilla - 8.3%. The following morphological types of DP (n = 118) were identified: hyperplastic DP - 49.2%, epithelial tumours - 16.1%, non-epithelial tumours - 1.7%, inflamed mucosal areas - 33.0%.
AuthorsM R Konorev, M E Matveenko, E L Katina
JournalKlinicheskaia meditsina (Klin Med (Mosk)) Vol. 90 Issue 12 Pg. 52-5 ( 2012) ISSN: 0023-2149 [Print] Russia (Federation)
PMID23516872 (Publication Type: Comparative Study, English Abstract, Journal Article)
Topics
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Diagnosis, Differential
  • Duodenum (pathology)
  • Endoscopy, Gastrointestinal
  • Female
  • Humans
  • Hyperplasia (pathology)
  • Incidence
  • Intestinal Mucosa (pathology)
  • Intestinal Polyps (diagnosis, epidemiology)
  • Male
  • Middle Aged
  • Republic of Belarus (epidemiology)
  • Retrospective Studies
  • Young Adult

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