Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromes.

Abstract

INTRODUCTION:

Identifying reperfusion and predicting post procedure risk is important following Percutaneous Coronary Interventions (PCI). An Angiographic Perfusion Score (APS) combining TIMI flow (TFG) and myocardial perfusion (TMPG) grades before and after PCI can accurately measure both epicardial and myocardial perfusion and predict Major Adverse Cardiac Events (MACE).

PATIENTS AND METHODS:

APS was calculated in 226 (88 ST elevation Myocardial Infarction (STEMI) and 138 Non STEMI) patients. Maximum score being 12, reperfusion was defined as failed: 0-3, partial: 4-9, and full APS: 10-12. Thirty day MACE were observed.

RESULTS:

APS identified reperfusion significantly more than TMPG alone (STEMI: 50.6% vs 11.8% (p < 0.001); Non STEMI, early reperfusion: 69.4% vs 52.8% (p < 0.01) and Non STEMI late reperfusion: 38.2% vs 7.8%; (p ≤ 0.001) respectively. A significantly lower incidence of MACE was observed in the full as compared to the failed APS group (1.8% vs 22.5%) (p < 0.001). No differences were noted between TMPG 0-2 (9.8%, 9.4%, 7.3%, respectively) (p = NS).

CONCLUSION:

Compared to MPG alone APS detects more low risk reperfused patients, post PCI.

• Authors: V S Narain, L Fischer, A Puri, R Sethi, S K Dwivedi
• Journal: Indian heart journal (Indian Heart J) 2013 Jan-Feb Vol. 65 Issue 1 Pg. 1-6 ISSN: 0019-4832 [Print] India
• PMID: 23438605 (Publication Type: Journal Article)
• Copyright: Copyright © 2012. Published by Elsevier B.V.

Topics

• Acute Coronary Syndrome (diagnostic imaging, therapy)
• Chi-Square Distribution
• Coronary Angiography
• Female
• Humans
• Male
• Middle Aged
• Myocardial Reperfusion (methods)
• Percutaneous Coronary Intervention
• Predictive Value of Tests
• Prognosis