Use of noninsulin antidiabetic medications in hospitalized patients.

Abstract

Noninsulin antidiabetic medications coupled with diet and exercise are effective in managing most patients with type 2 diabetes. However, it is essential to evaluate the safety and effectiveness of the home antidiabetic medication regimen when the patient is hospitalized. Prescribers need to be aware of the mechanism of action of each class, contraindications, precautions, and adverse effects to formulate a safe and effective management plan. This article details the different classes of noninsulin antidiabetic medications, the mechanism of action, metabolism, elimination, dose form, usual and maximum doses, contraindications, precautions, common adverse reactions, and implications for use in the hospitalized patient.

• Authors: Cori Kopecky
• Journal: Critical care nursing clinics of North America (Crit Care Nurs Clin North Am) Vol. 25 Issue 1 Pg. 39-53 (Mar 2013) ISSN: 1558-3481 [Electronic] United States
• PMID: 23410645 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2013 Elsevier Inc. All rights reserved.

Chemical References

• Benzamides
• Biguanides
• Dipeptidyl-Peptidase IV Inhibitors
• Glycoside Hydrolase Inhibitors
• Hypoglycemic Agents
• Incretins
• Islet Amyloid Polypeptide
• Sulfonylurea Compounds
• Thiazolidinediones
• Bromocriptine
• meglitinide
• Metformin

Topics

• Benzamides (pharmacology, therapeutic use)
• Biguanides (pharmacology, therapeutic use)
• Bromocriptine (administration & dosage, therapeutic use)
• Diabetes Mellitus (drug therapy, nursing)
• Dipeptidyl-Peptidase IV Inhibitors (administration & dosage, therapeutic use)
• Glycoside Hydrolase Inhibitors
• Hospitalization
• Humans
• Hypoglycemia (chemically induced)
• Hypoglycemic Agents (adverse effects, pharmacokinetics, pharmacology, therapeutic use)
• Incretins (administration & dosage, therapeutic use)
• Islet Amyloid Polypeptide (agonists)
• Metformin (pharmacology, therapeutic use)
• Sulfonylurea Compounds (administration & dosage, metabolism, therapeutic use)
• Thiazolidinediones (pharmacology, therapeutic use)