Acquired protein energy malnutrition in glutaric acidemia.

Abstract

We report a case of acquired protein energy malnutrition with associated zinc deficiency in an 18-month-old boy with type 1 glutaric acidemia. Physical examination findings included generalized nonpitting edema, widespread desquamative plaques, and sparse hair with a reddish tinge. Laboratory abnormalities included low levels of zinc, albumin, alkaline phosphatase, and iron. A review of skin manifestations of nutritional deficiencies, specifically kwashiorkor, is presented, as well as the relatively new entity called acrodermatitis dysmetabolica.

• Authors: Liqiao Ma, Stephanie Savory, Nnenna G Agim
• Journal: Pediatric dermatology (Pediatr Dermatol) 2013 Jul-Aug Vol. 30 Issue 4 Pg. 502-4 ISSN: 1525-1470 [Electronic] United States
• PMID: 23330977 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2013 Wiley Periodicals, Inc.

Chemical References

• Glutaryl-CoA Dehydrogenase
• Zinc

Topics

• Acrodermatitis (diagnosis)
• Amino Acid Metabolism, Inborn Errors (complications, diagnosis)
• Biopsy
• Brain Diseases, Metabolic (complications, diagnosis)
• Dermatitis (diagnosis, etiology)
• Diagnosis, Differential
• Glutaryl-CoA Dehydrogenase (deficiency)
• Humans
• Infant
• Kwashiorkor (diagnosis)
• Male
• Protein-Energy Malnutrition (diagnosis, etiology)
• Zinc (deficiency)