[Experimental study of osseointegration of nHA/BG coating and Bio-Oss in implant defects].

Abstract

PURPOSE:

To evaluate bone regeneration in defects at titanium implants with nHA/BG coating in conjunction with Bio-Oss.

METHODS:

Four mandibular premolars were extracted in 6 Beagle dogs. After 3 months, buccal dehiscence-type defects (2.25 mm×3 mm×4 mm) were surgically created following implant site. The three treatment modalities were randomly allocated: nHA/BG implant/Bio-Oss, nHA/BG implant/blood clot, and mHA implant/Bio-Oss. After 8 and 16 weeks, the dogs were sacrificed respectively. A histomorphometric analysis was performed. The data was analyzed with SPSS 13.0 software package for Student's t test and ANOVA.

RESULTS:

At 8- and 16-week, nHA/BG implant group revealed comparable mean BIC (30% to 18% versus 61% to 53%). However, mHA implant/Bio-Oss group revealed significantly lower mean BIC (21% versus 46%) values than nHA/BG implant/Bio-Oss group.A significant difference was observed for the mean BIC and RA values at 8-week between nHA/BG implant/Bio-Oss group and mHA implant/Bio-Oss group.

CONCLUSIONS:

It is concluded that the application of Bio-Oss graft did not seem to interfere with the nHA/BG coating activity, but ensured a stabilization of the newly formed bone for defects.

• Authors: Fei Sun, Ting-ting Lin, Xiao-ye Yuan, Shao-xian Zeng, Rui-lin DU, Er-yi Lu
• Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology (Shanghai Kou Qiang Yi Xue) Vol. 21 Issue 4 Pg. 378-83 (Aug 2012) ISSN: 1006-7248 [Print] China
• PMID: 23135110 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Bio-Oss
• Bone Substitutes
• Dental Implants
• Minerals
• Titanium

Topics

• Animals
• Bone Regeneration
• Bone Substitutes
• Dental Implantation, Endosseous
• Dental Implants
• Dogs
• Minerals
• Osseointegration
• Titanium