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Diminished superoxide anion generation by reduced 5-iminodaunorubicin relative to daunorubicin and the relationship to cardiotoxicity of the anthracycline antitumor agents.

AuthorsJ W Lown, H H Chen, J A Plambeck, E M Acton
JournalBiochemical pharmacology (Biochem Pharmacol) Vol. 28 Issue 17 Pg. 2563-8 (Sep 01 1979) ISSN: 0006-2952 [Print] England
PMID229856 (Publication Type: Journal Article)
Chemical References
  • DNA, Neoplasm
  • Superoxides
  • Hydrogen Peroxide
  • Oxygen
  • Daunorubicin
Topics
  • Chemical Phenomena
  • Chemistry
  • DNA, Neoplasm
  • Daunorubicin (analogs & derivatives, toxicity)
  • Drug Stability
  • Heart Diseases (chemically induced)
  • Hydrogen Peroxide
  • Oxygen
  • Superoxides
  • Time Factors

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