Abstract | OBJECTIVE: MATERIALS AND METHODS: 67 patients were randomly assigned to four treatment arms: monotherapy with atorvastatin, monotherapy with fenofibrate, combined therapy ( fenofibrate and torvastatin) or therapeutic lifestyle change. The study lasted for 90 days. All participants received counseling regarding proper diet and physical activity. RESULTS: CONCLUSIONS:
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Authors | Lukasz Buldak, Anna Dulawa-Buldak, Krzysztof Labuzek, Boguslaw Okopien |
Journal | International journal of clinical pharmacology and therapeutics
(Int J Clin Pharmacol Ther)
Vol. 50
Issue 11
Pg. 805-13
(Nov 2012)
ISSN: 0946-1965 [Print] Germany |
PMID | 22943927
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- ADIPOQ protein, human
- Adipokines
- Adiponectin
- Biomarkers
- Blood Glucose
- Cytokines
- Heptanoic Acids
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Hypolipidemic Agents
- IL6 protein, human
- Inflammation Mediators
- Insulin
- Interleukin-6
- Leptin
- Lipids
- Pyrroles
- RETN protein, human
- Resistin
- Tumor Necrosis Factor-alpha
- Atorvastatin
- Fenofibrate
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Topics |
- Adipokines
(blood)
- Adiponectin
(blood)
- Adult
- Aged
- Analysis of Variance
- Atorvastatin
- Biomarkers
(blood)
- Blood Glucose
(drug effects, metabolism)
- Cytokines
(blood)
- Drug Therapy, Combination
- Female
- Fenofibrate
(therapeutic use)
- Glucose Metabolism Disorders
(blood, diagnosis, drug therapy, immunology)
- Heptanoic Acids
(therapeutic use)
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
(therapeutic use)
- Hyperlipoproteinemia Type V
(blood, diagnosis, drug therapy, immunology)
- Hypolipidemic Agents
(therapeutic use)
- Inflammation Mediators
(blood)
- Insulin
(blood)
- Insulin Resistance
- Interleukin-6
(blood)
- Leptin
(blood)
- Lipids
(blood)
- Male
- Middle Aged
- Poland
- Pyrroles
(therapeutic use)
- Resistin
(blood)
- Risk Reduction Behavior
- Time Factors
- Treatment Outcome
- Tumor Necrosis Factor-alpha
(blood)
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