Abstract | BACKGROUND: OBJECTIVE: To present the outcomes of all patients undergoing reoperative hemispherectomy in 1 institution by 1 surgeon since 1998. METHODS: The medical records, operative reports, and imaging studies for 36 patients undergoing reoperative hemispherectomy for continuing medically intractable epilepsy from 1998 to 2011 at Cleveland Clinic were reviewed. Patient characteristics, cause of seizure, imaging findings, surgery-related complications, and long-term seizure outcomes were evaluated. RESULTS: CONCLUSION: The possibility that residual epileptogenic tissue in the operated hemisphere remains connected should be considered after failed functional hemispherectomy because our data suggest that improvement in seizure frequency is possible after reoperative hemispherectomy, although the chance of obtaining seizure freedom is relatively low. The decision to proceed with reoperative hemispherectomy should be made after proper discussion with the patient and family and informed consent is given.
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Authors | Sumeet Vadera, Ahsan N V Moosa, Lara Jehi, Ajay Gupta, Prakash Kotagal, Deepak Lachhwani, Elaine Wyllie, William Bingaman |
Journal | Neurosurgery
(Neurosurgery)
Vol. 71
Issue 2
Pg. 388-92; discussion 392-3
(Aug 2012)
ISSN: 1524-4040 [Electronic] United States |
PMID | 22513844
(Publication Type: Clinical Trial, Journal Article)
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Topics |
- Adolescent
- Adult
- Child
- Child, Preschool
- Chronic Disease
- Epilepsy
(diagnosis, surgery)
- Female
- Hemispherectomy
(methods)
- Humans
- Infant
- Male
- Reoperation
- Treatment Outcome
- Young Adult
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