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[Valproic acid and stupor].

Abstract
A patient treated with valproic acid and phenytoin for complex partial epilepsy developed a stupor at therapeutic serum levels of the anti-epileptic agents. A few days after discontinuation of valproic acid, complete recovery occurred. The pathogenic mechanism involved is still obscure.
AuthorsM J Jongsma, C J Snijders
JournalNederlands tijdschrift voor geneeskunde (Ned Tijdschr Geneeskd) Vol. 134 Issue 43 Pg. 2105-6 (Oct 27 1990) ISSN: 0028-2162 [Print] Netherlands
Vernacular TitleValproïnezuur en stupor.
PMID2234190 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Valproic Acid
  • Phenytoin
Topics
  • Drug Therapy, Combination
  • Epilepsy, Temporal Lobe (drug therapy)
  • Humans
  • Male
  • Middle Aged
  • Phenytoin (administration & dosage, therapeutic use)
  • Unconsciousness (chemically induced)
  • Valproic Acid (administration & dosage, adverse effects)

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