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Elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, and idarubicin combination is active in refractory acute myeloid leukemia.

AuthorsFrancis Giles, David Rizzieri, Farhad Ravandi, Ronan Swords, Tove Flem Jacobsen, Susan O'Brien
JournalLeukemia research (Leuk Res) Vol. 36 Issue 4 Pg. e71-3 (Apr 2012) ISSN: 1873-5835 [Electronic] England
PMID22226018 (Publication Type: Clinical Trial, Phase I, Letter, Multicenter Study)
Chemical References
  • Cytarabine
  • 5'-oleoyl cytarabine
  • Idarubicin
Topics
  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols (pharmacokinetics, therapeutic use)
  • Area Under Curve
  • Cytarabine (administration & dosage, adverse effects, analogs & derivatives, pharmacokinetics)
  • Female
  • Half-Life
  • Humans
  • Idarubicin (administration & dosage, adverse effects, pharmacokinetics)
  • Leukemia, Myeloid, Acute (drug therapy)
  • Male
  • Maximum Tolerated Dose
  • Middle Aged
  • Young Adult

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