Abstract | INTRODUCTION AND HYPOTHESIS: This study was designed to evaluate clinical outcomes ≥2 years following surgery with polypropylene mesh and vaginal support device (VSD) in women with vaginal prolapse, in a prospective, multi-center setting. METHODS: Patients re-consented for this extended follow-up (n = 110), with anatomic evaluation using Pelvic Organ Prolapse Quantification (POP-Q) and validated questionnaires to assess pelvic symptoms and sexual function. Complications were recorded (safety set; n = 121). RESULTS: Median length of follow-up was 29 months (range 24-34 months). The primary anatomic success, defined as POP-Q 0-I, was 69.1%; however, in 84.5% of the cases, the leading vaginal edge was above the hymen. Pelvic symptoms and sexual function improved significantly from baseline (p < 0.01). Mesh exposure rate was 9.1%. Five percent reported stress urinary incontinence and 3.3% required further prolapse surgery. CONCLUSION: These results indicate this non-anchored mesh repair is a safe and effective treatment for women with symptomatic vaginal prolapse in the medium term.
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Authors | T Sayer, J Lim, J M Gauld, P Hinoul, P Jones, N Franco, D Van Drie, M Slack, Prosima Study Investigators |
Journal | International urogynecology journal
(Int Urogynecol J)
Vol. 23
Issue 4
Pg. 487-93
(Apr 2012)
ISSN: 1433-3023 [Electronic] England |
PMID | 22143448
(Publication Type: Journal Article, Multicenter Study)
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Chemical References |
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Topics |
- Aged
- Cohort Studies
- Female
- Follow-Up Studies
- Gynecologic Surgical Procedures
(instrumentation, methods)
- Humans
- Middle Aged
- Polypropylenes
- Suburethral Slings
(adverse effects)
- Surgical Mesh
(adverse effects)
- Surveys and Questionnaires
- Treatment Outcome
- Uterine Prolapse
(surgery)
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