Abstract |
In 4 young pediatric patients with presymptomatic Wilson disease, we found zinc monotherapy beginning at time of diagnosis to be safe and highly effective for follow-up intervals between 1 and 2 years. Such maintenance therapy with zinc can maintain urinary copper excretion between 1 and 3 μg · kg(-1) · day.
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Authors | Tatsuki Mizuochi, Akihiko Kimura, Norikazu Shimizu, Hiroshi Nishiura, Masami Matsushita, Makoto Yoshino |
Journal | Journal of pediatric gastroenterology and nutrition
(J Pediatr Gastroenterol Nutr)
Vol. 53
Issue 4
Pg. 365-7
(Oct 2011)
ISSN: 1536-4801 [Electronic] United States |
PMID | 21970993
(Publication Type: Journal Article)
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Chemical References |
- Copper
- Aspartate Aminotransferases
- Alanine Transaminase
- Zinc
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Topics |
- Alanine Transaminase
(blood)
- Aspartate Aminotransferases
(blood)
- Asymptomatic Diseases
(therapy)
- Child
- Child, Preschool
- Copper
(blood, urine)
- Female
- Follow-Up Studies
- Hepatolenticular Degeneration
(diagnosis, drug therapy)
- Humans
- Zinc
(therapeutic use)
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