Recurrence of erythema induratum of Bazin in a patient under chemotherapy for breast cancer.

Abstract

Erythema induratum of Bazin (EIB) is a chronic nodular eruption occurring on the lower legs of young and middleaged women which is considered the most common tuberculid. A 54-year-old woman, in treatment with chemotherapy for breast cancer, presented subcutaneous erythematous plaques and nodules on the lower limbs. She had been diagnosed with EIB 3 years earlier and diagnostic work-up showed at that time signs suggestive of latent tuberculosis. The suspect of a recurrent form of EIB was confirmed by histopathological examination. A peculiar feature of our report consists in the recurrence of EIB, which is regarded as a hyperergic response against M. tuberculosis antigens, in a patient who was receiving chemotherapy with well-known immunosuppressive effects.

• Authors: Gino A Vena, Doriana Apruzzi, Michelangelo Vestita, Maria Panaro, Simona Carpagnano, Ruggero Filannino, Nicoletta Cassano
• Journal: The new microbiologica (New Microbiol) Vol. 34 Issue 3 Pg. 331-3 (Jul 2011) ISSN: 1121-7138 [Print] Italy
• PMID: 21811756 (Publication Type: Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Antineoplastic Agents (therapeutic use)
• Breast Neoplasms (drug therapy, microbiology)
• Erythema Induratum (diagnosis)
• Female
• Humans
• Middle Aged
• Mycobacterium tuberculosis (drug effects, pathogenicity)