Cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm.

Abstract

We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z-Phe-Ala. It was lower on Z-Phe-Phe, Z-Glu-Tyr, Z-Glu-Phe, Z-Gly-Phe, and the lowest activity was on Z-Gly-Ala. We conclude that cathepsin A's activity on a parietal thrombus of an aneurysm is much higher than blood clot cathepsin A activity.

• Authors: Marta Siergiejuk, Marek Gacko, Anna Worowska
• Journal: Folia histochemica et cytobiologica (Folia Histochem Cytobiol) Vol. 49 Issue 1 Pg. 10-2 ( 2011) ISSN: 1897-5631 [Electronic] Poland
• PMID: 21526484 (Publication Type: Journal Article, Review)

Chemical References

• Cathepsin A

Topics

• Aged
• Aortic Aneurysm, Abdominal (enzymology, surgery)
• Cathepsin A (metabolism)
• Female
• Humans
• Male
• Thrombosis (enzymology)