Coronary artery spasm during angiography in a pediatric heart transplant recipient: subsequent prevention by intracoronary nitroglycerin administration.

Abstract

Coronary artery spasm can occur during coronary angiography in pediatric heart transplant recipients. The angiographic appearance can suggest allograft vasculopathy. We report coronary artery spasm in a pediatric heart transplant recipient in whom intracoronary nitroglycerin administration prevented a repetition of spasm upon subsequent diagnostic coronary angiography. Additional studies of dose response, particularly in cardiac transplant recipients, may help determine whether lower doses of intracoronary nitrates, such as that administered to our patient, can be effective in preventing coronary artery vasospasm in pediatric heart transplant recipients.

• Authors: Matthew E Ferguson, F Bennett Pearce, Hao H Hsu, Vijay K Misra, James K Kirklin
• Journal: Texas Heart Institute journal (Tex Heart Inst J) Vol. 37 Issue 4 Pg. 469-71 ( 2010) ISSN: 1526-6702 [Electronic] United States
• PMID: 20844625 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vasodilator Agents
• Nitroglycerin

Topics

• Child
• Coronary Angiography (adverse effects)
• Coronary Vasospasm (diagnostic imaging, etiology, prevention & control)
• Heart Transplantation
• Humans
• Injections, Intra-Arterial
• Male
• Nitroglycerin (administration & dosage)
• Vasodilator Agents (administration & dosage)