A case of chronic progressive myelopathy.

Abstract

Acute myelitis and optic neuritis are the main clinical features of patients with neuromyelitis optica (NMO), which usually appears as a relapsing-remitting course of disease that worsens over days and improves over weeks. We present a patient with chronic progressive myelitis over a 4-month period without remission as having a limited form of NMO that improved after plasmapheresis. Plasmapheresis may benefit patients with chronic progressive myelitis, which may be a manifestation of NMO, as well as those with a relapsing-remitting course of NMO.

• Authors: Jun-Soon Kim, Young Ho Park, Sung-Min Kim, Su-hyun Kim, Kyung Seok Park, Jung-Joon Sung, Kwang-Woo Lee
• Journal: Multiple sclerosis (Houndmills, Basingstoke, England) (Mult Scler) Vol. 16 Issue 10 Pg. 1255-7 (Oct 2010) ISSN: 1477-0970 [Electronic] England
• PMID: 20798133 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Aquaporin 4
• Autoantibodies
• Methylprednisolone

Topics

• Anti-Inflammatory Agents (therapeutic use)
• Aquaporin 4 (immunology)
• Autoantibodies (analysis)
• Humans
• Magnetic Resonance Imaging
• Male
• Methylprednisolone (therapeutic use)
• Middle Aged
• Muscle Strength (physiology)
• Neurologic Examination
• Neuromyelitis Optica (drug therapy, pathology, therapy)
• Plasmapheresis
• Spinal Cord (pathology)