Four cases of facial discoid lupus erythematosus successfully treated with topical pimecrolimus or tacrolimus.

Abstract

Discoid lupus erythematosus (DLE), which is a cutaneous form of lupus erythematosus (LE), is generally refractory to a wide range of topical or systemic therapies. Although the main treatment option for DLE is topical steroids, it is often ineffective or likely to produce long-term side effects. New drugs, including tacrolimus and pimecrolimus, have been developed to overcome the adverse effects of steroids and treat the lesions of DLE for a prolonged period. We herein report 4 cases of facial DLE successfully treated with therapeutic adjuvants, topical tacrolimus or pimecrolimus.

• Authors: Ye Won Han, Hyung Ok Kim, Sung Hwan Park, Young Min Park
• Journal: Annals of dermatology (Ann Dermatol) Vol. 22 Issue 3 Pg. 307-11 (Aug 2010) ISSN: 2005-3894 [Electronic] Korea (South)
• PMID: 20711267 (Publication Type: Case Reports)