Ocular malformation in a newborn secondary to maternal hypovitaminosis A.

Abstract

We report a case of microphthalmia, inferior adherent leukoma, and optic nerve hypoplasia in an infant whose mother underwent biliopancreatic diversion surgery for obesity 7 years before his birth. The pregnancy was complicated by severe, maternal hypovitaminosis A despite oral supplementation. The infant was found to have undetectable serum vitamin A levels in the perinatal period. At 8 weeks of age, the infant underwent sector iridectomies. At 9 months of age, electroretinography suggested rod dysfunction. His visual performance is poor.

• Authors: Hannah Gilchrist, Deepa A Taranath, Glen A Gole
• Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 14 Issue 3 Pg. 274-6 (Jun 2010) ISSN: 1528-3933 [Electronic] United States
• PMID: 20603063 (Publication Type: Case Reports, Journal Article)

Topics

• Eye Abnormalities (etiology)
• Female
• Gastric Bypass (adverse effects)
• Humans
• Infant
• Infant, Newborn
• Male
• Night Blindness (etiology)
• Obesity, Morbid (surgery)
• Pregnancy
• Pregnancy Complications
• Prenatal Exposure Delayed Effects (etiology)
• Vitamin A Deficiency (complications, etiology)