Abstract | OBJECTIVE: METHODS: Forty patients with allergic conjunctivitis were included in the study, they were randomized in two groups: G-I (n = 20) olopatadine 0.1 % and G-II (n = 20) ketotifen 0.025 %, both receiving one drop every 12 hours. We evaluated itching, burning, tearing, redness and chemosis previously and 30 minutes, one, two and four week after. RESULTS: Age G-I was 19.7 +/- 6.7 years; G-II, 21.05 +/- 8.3 years. When evaluating itching, olopatadine had a significant improvement at 30 minutes and after one week (p < 0.05). In the following weeks, the results were similar in both groups. Olopatadine showed significant improvement in burning at 30 minutes, one and two week (p < 0.05). Tearing significantly decreased at 30 minutes with olopatadine (p < 0.05). There was no difference in redness or chemosis improvement in both groups. CONCLUSIONS:
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Authors | Massiel Elena Varguez-Rodríguez, Adriana Hernández-López, Rocío de Los Angeles Gómez-Dávila |
Journal | Revista medica del Instituto Mexicano del Seguro Social
(Rev Med Inst Mex Seguro Soc)
2009 Jul-Aug
Vol. 47
Issue 4
Pg. 399-404
ISSN: 0443-5117 [Print] Mexico |
Vernacular Title | Olopatadina y ketotifeno para tratar conjuntivitis alérgica. |
PMID | 20553645
(Publication Type: Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anti-Allergic Agents
- Dibenzoxepins
- Olopatadine Hydrochloride
- Ketotifen
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Topics |
- Anti-Allergic Agents
(therapeutic use)
- Conjunctivitis, Allergic
(drug therapy)
- Dibenzoxepins
(therapeutic use)
- Female
- Humans
- Ketotifen
(therapeutic use)
- Male
- Olopatadine Hydrochloride
- Young Adult
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