Effect of PTSD diagnosis and contingency management procedures on cocaine use in dually cocaine- and opioid-dependent individuals maintained on LAAM: a retrospective analysis.

Abstract

This randomized clinical trial retrospectively examined the effect of post-traumatic stress disorder (PTSD) and contingency management (CM) on cocaine use in opioid and cocaine dependent individuals maintained on high or low-dose LAAM randomly assigned to CM or a yoked-control condition. Cocaine-positive urines decreased more rapidly over time in those without PTSD versus those with PTSD in the noncontingency condition. In participants with PTSD, CM resulted in fewer cocaine-positive urines compared to the noncontingent condition. This suggests that CM may help improve the potentially worse outcomes in opioid- and cocaine-dependent individuals with PTSD compared to those without PTSD. (Am J Addict 2010;00:1-9).

• Authors: Michael J Mancino, Janette McGaugh, Zachary Feldman, James Poling, Alison Oliveto
• Journal: The American journal on addictions (Am J Addict) 2010 Mar-Apr Vol. 19 Issue 2 Pg. 169-77 ISSN: 1521-0391 [Electronic] England
• PMID: 20163389 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Methadyl Acetate

Topics

• Adult
• Behavior Therapy (methods)
• Cocaine-Related Disorders (complications, drug therapy, therapy, urine)
• Combined Modality Therapy (psychology)
• Diagnosis, Dual (Psychiatry) (statistics & numerical data)
• Dose-Response Relationship, Drug
• Female
• Humans
• Male
• Methadyl Acetate (administration & dosage)
• Opioid-Related Disorders (complications, drug therapy, therapy)
• Patient Compliance (statistics & numerical data)
• Retrospective Studies
• Stress Disorders, Post-Traumatic (complications, drug therapy, therapy)