Intrauterine device or estrogen treatment after hysteroscopic uterine septum resection.

Abstract

OBJECTIVE:

To investigate the effects on adhesion formation and pregnancy maintenance of an intrauterine device (IUD) and/or estrogen treatment after hysteroscopic septum resection.

METHODS:

After septum resection 100 women received either no treatment, or estrogens, or an IUD, or an IUD plus estrogens (n=25 per group). Most were later checked hysteroscopically for uterine cavity adhesions. All pregnancies occurring during the study period were recorded.

RESULTS:

Adhesions developed in 1 of 19 (5.3%) of the untreated women, 3 of 25 (12%) of the women treated with an IUD plus estrogens, 2 of 19 (10.5%) of the women treated with an IUD only, and none of the women treated with estrogens only. None of the differences, however, were significant. Regarding pregnancy, the differences between groups were also not significant.

CONCLUSION:

Neither IUD placement, nor estrogen treatment, nor both were found to prevent intrauterine adhesions or facilitate pregnancy after hysteroscopic uterine septum resection.

• Authors: Esra Ayşin Tonguc, Turgut Var, Nafiye Yilmaz, Sertac Batioglu
• Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (Int J Gynaecol Obstet) Vol. 109 Issue 3 Pg. 226-9 (Jun 2010) ISSN: 1879-3479 [Electronic] United States
• PMID: 20152976 (Publication Type: Comparative Study, Journal Article)
• Copyright: Copyright 2010 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Chemical References

• Contraceptives, Oral, Combined
• Drug Combinations
• Norgestrel
• Estradiol

Topics

• Adult
• Combined Modality Therapy
• Contraceptives, Oral, Combined (administration & dosage, therapeutic use)
• Drug Combinations
• Estradiol (administration & dosage, analogs & derivatives, therapeutic use)
• Female
• Humans
• Hysteroscopy (methods)
• Intrauterine Devices
• Norgestrel (administration & dosage, therapeutic use)
• Pregnancy
• Pregnancy Outcome
• Prospective Studies
• Single-Blind Method
• Tissue Adhesions (etiology, prevention & control)
• Uterus (abnormalities, surgery)
• Young Adult