Self-assembled monolayers of bisphosphonates: influence of side chain steric hindrance.

Abstract

Bisphosphonates form self-assembled monolayers (SAMs) spontaneously on stainless steel, silicon, and titanium oxidized surfaces. We used contact angle measurements, atomic force microscopy, and X-ray reflectivity analysis to study the formation of SAMs on a model surface of ultraflat titanium (rms = 0.2 nm). The results were extended to standard materials (mechanically polished titanium, stainless steel, and silicon) and showed that water-soluble bisphosphonic perfluoropolyether can easily form SAMs, with 100% surface coverage and a layer thickness of less than 3 nm. Hydrophobic (water contact angle >110 degrees on stainless steel or titanium) and lipophobic (methylene iodide contact angle >105 degrees on titanium) properties are discussed in terms of industrial applications.

• Authors: G Lecollinet, N Delorme, M Edely, A Gibaud, J-F Bardeau, F Hindré, F Boury, D Portet
• Journal: Langmuir : the ACS journal of surfaces and colloids (Langmuir) Vol. 25 Issue 14 Pg. 7828-35 (Jul 21 2009) ISSN: 0743-7463 [Print] United States
• PMID: 19555050 (Publication Type: Journal Article)