Diffuse lupus encephalopathy in a case of rhupus syndrome.

Abstract

"Rhupus syndrome" is a rare clinical condition, which is related to anti-CCP antibody, characterized by overlapping clinical and immunologic features of rheumatoid arthritis and systemic lupus erythematosus. Previous reports mentioned that patients have more RA-associated damage, and little organic damage associated with SLE. The severe organ damage, especially central nervous system involvement has been reported to be rare in patients with rhupus syndrome. Here, we report a very rare concurrence of RA, SLE and diffuse lupus encephalopathy in a Chinese woman.

• Authors: Jian-Gang Wang, He-Han Tang, Chun-Yu Tan, Yi Liu, Hui Lin, Yong-Tao Chen
• Journal: Rheumatology international (Rheumatol Int) Vol. 30 Issue 7 Pg. 961-3 (May 2010) ISSN: 1437-160X [Electronic] Germany
• PMID: 19536547 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Methylprednisolone

Topics

• Adult
• Anti-Inflammatory Agents (therapeutic use)
• Arthritis, Rheumatoid (complications, pathology, physiopathology)
• Asian People
• Brain (pathology, physiopathology)
• Encephalitis (immunology, pathology, physiopathology)
• Female
• Humans
• Joints (pathology, physiopathology)
• Lupus Vasculitis, Central Nervous System (immunology, pathology, physiopathology)
• Magnetic Resonance Imaging
• Methylprednisolone (therapeutic use)
• Nerve Fibers, Myelinated (pathology)
• Seizures (drug therapy, etiology)
• Treatment Outcome