Abstract |
Integra Artificial Skin, a biosynthetic dermal template, is well established in acute burn surgery. The aim of the study was to determine the role of Integra in the surgical treatment of postburn scars in a younger population. Between March 1998 and November 2004, 17 patients (n=17; mean age=13.15 years) underwent complete excision of hypertrophic scars or keloids (1-4% TBSA; extremities=47%, head/neck=35%, trunk=18%) with subsequent implantation of Integra for defect closure. Split thickness skin grafting (STSG) of the Integra-derived neodermis was performed 3 weeks after the first operation. Scar excision and primary Integra implantation was successful in all but one patient (94%) who (6%) needed reimplantation once. Integra's mean take rate was 99.7% for all primarily successful patients. Complications occurred in three patients (18%), including minor problems without long-term consequences in 12% ( seroma formation), and major problems in 6% ( hematoma formation). Take rate of STSG ranged from 50% to 100% (mean 94%). Functional and cosmetic long-term outcome showed results scored "excellent" in 53%, "good" in 36%, and "fair" in 11%. Comparison of pre- and postoperative findings revealed a significant functional improvement in all and a considerable cosmetic improvement in all but two patients. These results suggest that Integra is a valid new treatment modality for extensive burn scar revision in younger patients.
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Authors | Dorothea Stiefel, Clemens Schiestl, Martin Meuli |
Journal | Burns : journal of the International Society for Burn Injuries
(Burns)
Vol. 36
Issue 1
Pg. 114-20
(Feb 2010)
ISSN: 1879-1409 [Electronic] Netherlands |
PMID | 19477602
(Publication Type: Evaluation Study, Journal Article)
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Copyright | Copyright (c) 2009 Elsevier Ltd and ISBI. All rights reserved. |
Chemical References |
- integra artificial skin
- Chondroitin Sulfates
- Collagen
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Topics |
- Adolescent
- Burns
(complications, pathology, surgery)
- Child
- Chondroitin Sulfates
(adverse effects, therapeutic use)
- Cicatrix, Hypertrophic
(etiology, parasitology, surgery)
- Collagen
(adverse effects, therapeutic use)
- Esthetics
- Female
- Humans
- Keloid
(etiology, pathology, surgery)
- Male
- Plastic Surgery Procedures
(methods)
- Reoperation
(methods)
- Skin, Artificial
- Treatment Outcome
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