Abstract |
The effect on pulmonary function of serial VEPTR expansion thoracoplasty was studied longitudinally in anesthetized children with spondylothoracic dysplasia using a special mobile unit. The median age of 24 children at the start of surgery was 4.6 years (1.8-10.8) and most exhibited a moderate-to-severe restrictive lung defect. After a median of 3.2 years (1.0-6.5), their forced vital capacity (FVC) was found to have increased by an average of 11.1%/year. The rate of increase was greater in children who were younger than 6 years at the start of the study than in older children (14.5% versus 6.5%, p<0.01). The average specific respiratory system compliance (C(rs)) was mildly-to-moderately decreased at the start, and over the study it decreased on average to 56% of the initial value in spite of clinically successful expansion thoracoplasty and lung growth, indicating increasing stiffness of the thorax with growth.
|
Authors | Etsuro K Motoyama, Charles I Yang, Vincent F Deeney |
Journal | Paediatric respiratory reviews
(Paediatr Respir Rev)
Vol. 10
Issue 1
Pg. 12-7
(Mar 2009)
ISSN: 1526-0550 [Electronic] England |
PMID | 19203739
(Publication Type: Journal Article)
|
Topics |
- Age of Onset
- Child
- Child, Preschool
- Female
- Humans
- Infant
- Lung
(physiopathology)
- Male
- Musculoskeletal Abnormalities
(complications, surgery)
- Scoliosis
(complications, surgery)
- Thoracoplasty
- Treatment Outcome
- Vital Capacity
|