[Familial summer-type hypersensitivity pneumonitis in a husband and wife].

Abstract

We encountered a family in which two of four members, the husband and his wife, had summer-type hypersensitivity pneumonitis at the same time, about two months after they moved to the residence. A 45-year-old man had cough, fever and exertional dyspnea. Chest computed tomography showed diffuse centriloblar ground-glass attenuation in both lung fields. His 43-year-old wife had chest small nodular shadows and similar symptoms to his husband. Serum anti-Tricosporon cutaneum (T. asahi: serotype II and T. mucoides: serotype I) antibodies of both patients were at the positive level. They were given diagnosis as summer-type hypersensitivity pneumonitis by radiological, serological and histological examinations. The symptoms in both cases were improved immediately after administration of systemic corticosteroid. Summer-type hypersensitivity pneumonitis was assumed to be caused for about two months duration of expousure to antigen.

• Authors: Yuka Amemiya, Ryo Shirai, Syunji Ando, Hiroyuki Fujii, Atsuko Iwata, Naoko Kai, Satoshi Otani, Kenji Umeki, Hiroshi Ishii, Jun-Ichi Kadota
• Journal: Arerugi = [Allergy] (Arerugi) Vol. 57 Issue 11 Pg. 1182-7 (Nov 2008) ISSN: 0021-4884 [Print] Japan
• PMID: 19052513 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Adrenal Cortex Hormones
• Antibodies, Fungal
• Antigens, Fungal
• Biomarkers

Topics

• Adrenal Cortex Hormones (administration & dosage)
• Adult
• Alveolitis, Extrinsic Allergic (diagnosis, drug therapy, etiology)
• Antibodies, Fungal (blood)
• Antigens, Fungal (adverse effects)
• Biomarkers (blood)
• Environmental Exposure (adverse effects)
• Female
• Humans
• Lung (pathology)
• Male
• Middle Aged
• Spouses
• Tomography, X-Ray Computed
• Treatment Outcome
• Trichosporon (immunology, pathogenicity)