Abstract | BACKGROUND: Combination injectable contraceptives provide a highly effective, reversible method of preventing pregnancy, and they do not require daily administration or use at the time of coitus. Although they are used in many countries, their acceptability could be limited by method characteristics, such as the need to obtain a monthly injection or bleeding pattern changes. OBJECTIVES: SEARCH STRATEGY: SELECTION CRITERIA: DATA COLLECTION AND ANALYSIS: One author evaluated all titles and abstracts from the literature searches to determine their eligibility. Two authors independently extracted data from the eligible trials. Data on contraceptive efficacy, bleeding patterns, continuation, and side effects were entered and analyzed with RevMan. MAIN RESULTS: AUTHORS' CONCLUSIONS: While discontinuation rates can be viewed as a measure of method acceptability, the findings should be interpreted with caution since discontinuation depends on many factors. Future research should be directed toward interventions to improve the acceptability of combination injectable contraceptives, such as providing injections in settings more convenient than clinics, methods for women to administer their own injections, and counseling about possible bleeding pattern changes.
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Authors | Maria F Gallo, David A Grimes, Laureen M Lopez, Kenneth F Schulz, Catherine d'Arcangues |
Journal | The Cochrane database of systematic reviews
(Cochrane Database Syst Rev)
Issue 4
Pg. CD004568
(Oct 08 2008)
ISSN: 1469-493X [Electronic] England |
PMID | 18843662
(Publication Type: Journal Article, Review, Systematic Review)
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Chemical References |
- Contraceptive Agents, Female
- Drug Combinations
- Algestone
- Estradiol
- Medroxyprogesterone
- Norethindrone
- Megestrol Acetate
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Topics |
- Algestone
(administration & dosage)
- Contraception
(methods)
- Contraceptive Agents, Female
(administration & dosage, adverse effects)
- Drug Combinations
- Estradiol
(administration & dosage)
- Female
- Humans
- Injections
- Medication Adherence
- Medroxyprogesterone
(administration & dosage)
- Megestrol Acetate
(administration & dosage)
- Norethindrone
(administration & dosage)
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