HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Comparative study of higher-order aberrations after conventional laser in situ keratomileusis and laser epithelial keratomileusis for myopia using the technolas 217z laser platform.

AbstractPURPOSE:
To examine changes in higher-order aberrations (HOAs) after PlanoScan laser in situ keratomileusis and (LASIK) and laser epithelial keratomileusis (LASEK).
DESIGN:
Prospective, comparative study.
METHODS:
Myopic patients undergoing LASIK (65 eyes of 36 patients) and LASEK (50 eyes of 28 patients) at a private practice were selected randomly. Surgery was performed using the Technolas 217z laser (Bausch & Lomb, Surrey, United Kingdom). Main outcome measures included uncorrected visual acuity (UCVA), manifest refractive spherical equivalent (MRSE), and aberrometry (Zywave; Bausch & Lomb, Rochester, New York, USA) and were recorded before surgery and at three and 12 months after surgery.
RESULTS:
There was no statistical difference between both groups in terms of MRSE (P = .91), ablation depth (P = .47), scotopic pupil size (P = .38), or optical zone (P = .07). Before surgery, there was no statistical difference in root mean square (RMS) of total (P = .70), third- (P = .79), fourth- (P = .23), and fifth- (P = .33) order aberrations and individual terms. Three months after surgery, RMS of total HOA was raised significantly more (P = .03) after LASIK (1.46-factor increase) than LASEK (1.25-factor increase). One year after surgery, a reduction in total HOAs was observed in 13.8% of LASIK- and 48.5% of LASEK-treated eyes compared with preoperative levels.
CONCLUSIONS:
Postoperative increases in total HOA and vertical coma were significantly greater in LASIK- than in LASEK-treated eyes. Postoperative reduction in total HOAs was observed in a number of eyes with high preoperative levels and occurred more frequently in LASEK-treated eyes.
AuthorsCaitriona Kirwan, Michael O'Keefe
JournalAmerican journal of ophthalmology (Am J Ophthalmol) Vol. 147 Issue 1 Pg. 77-83 (Jan 2009) ISSN: 1879-1891 [Electronic] United States
PMID18775529 (Publication Type: Comparative Study, Journal Article)
Topics
  • Adult
  • Corneal Topography
  • Humans
  • Keratectomy, Subepithelial, Laser-Assisted
  • Keratomileusis, Laser In Situ
  • Lasers, Excimer (therapeutic use)
  • Middle Aged
  • Myopia (physiopathology, surgery)
  • Postoperative Complications
  • Prospective Studies
  • Refraction, Ocular
  • Refractive Errors (etiology, physiopathology)
  • Visual Acuity (physiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: