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Non-epithelial cellular components in eccrine spiradenoma: a histological and immunohistochemical study of 20 cases.

Abstract
In this study, 20 cases of eccrine spiradenoma have been examined using monoclonal antibodies to identify the nature of the epithelial, as well as the non-epithelial, cellular components of this tumour. The results indicate that there is striking similarity between the epithelial cells of eccrine spiradenoma and the normal cells lining eccrine apparatus. An interesting finding was the presence of abundant T-lymphocytes and Langerhans' cells within the tumour lobules. Additionally, endothelial-lined vascular channels and neurofibrils were prominent in larger lesions.
AuthorsA al-Nafussi, K Blessing, M Rahilly
JournalHistopathology (Histopathology) Vol. 18 Issue 2 Pg. 155-60 (Feb 1991) ISSN: 0309-0167 [Print] England
PMID1849119 (Publication Type: Journal Article)
Chemical References
  • Antibodies, Monoclonal
  • S100 Proteins
Topics
  • Adenoma, Sweat Gland (pathology)
  • Antibodies, Monoclonal
  • Eccrine Glands (pathology)
  • Epithelial Cells
  • Humans
  • Immunohistochemistry
  • S100 Proteins (analysis)

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