May-Thurner syndrome will be completed?

Abstract

BACKGROUND:

The May-Thurner syndrome is a deep venous thrombosis of the left iliofemoral vein due to a compression by the right primitive iliac artery. Some authors suggested that this syndrome could be associated with genetics factors predisposing to thrombophilia.

OBJECTIVES:

The aim of this article is to assess if the May-Thurner syndrome could be associated with inherited thombophilia particularly the factor V mutation.

PATIENTS/METHODS:

We exposed three cases of May-Thurner syndrome, all were positive for the presence of factor V Leiden.

CONCLUSION:

Some olds syndromes can be revisited and explained by molecular research. In this case, the May-Thurner syndrome could be associated with inherited thrombophilia. This finding could explain the pathology but also open new treatments or guidelines for the management this kind of pathology.

• Authors: Yann De Bast, Laurent Dahin
• Journal: Thrombosis research (Thromb Res) Vol. 123 Issue 3 Pg. 498-502 ( 2009) ISSN: 0049-3848 [Print] United States
• PMID: 18479739 (Publication Type: Case Reports, Journal Article)

Chemical References

• factor V Leiden
• Factor V
• Prothrombin

Topics

• Adolescent
• Adult
• Factor V (genetics)
• Female
• Femoral Vein
• Humans
• Iliac Artery
• Ilium
• Lumbosacral Region
• Point Mutation
• Prothrombin (genetics)
• Syndrome
• Thrombophilia (blood, complications, genetics)
• Tomography, X-Ray Computed
• Venous Thrombosis (blood, diagnostic imaging, etiology, genetics)
• Young Adult