[Diagnosis and treatment of non-specific granulomatous prostatitis: a report of 32 cases].

Abstract

OBJECTIVE:

To discuss the diagnosis and treatment of non-specific granulomatous prostatitis (NSGP).

METHODS:

Thirty-two cases of NSGP were diagnosed by puncture biopsy under transrectal ultrasound (TRUS) and treated with antibiotics and other medicines from September, 2000 to May, 2006.

RESULTS:

Pathomorphologically, NSGP was basically characterized by granuloma with vessels or grand alveoli in the center. The mean follow-up was 24 months. Urination irritation and obstruction were improved. Q(max) was increased to 15.0-24.0 ml/s, and in 3 cases of urinary retention, to 12.0, 14.5 and 16.5 ml/s, respectively. Digital rectal examination (DRE) indicated a reduced size and softened texture of the prostate induration. PSA was decreased to 1.3-11.5 microg/L. Four cases experienced relapse but were cured after retreated. No prostate cancer was observed.

CONCLUSION:

NSGP can be definitely diagnosed by puncture biopsy under TRUS and effectively relieved by antibiotics with the alpha-receptor blocker. In case of serious obstruction complicated by urinary retention, transurethral electrotomy can be considered.

• Authors: Hai-Tao Fan, Kai-Chen Wang, Mu-Chun Zhang, Wei-Hua Wang, Guo-Yi Ji, Yao Wang, Xiang-Bo Kong
• Journal: Zhonghua nan ke xue = National journal of andrology (Zhonghua Nan Ke Xue) Vol. 14 Issue 2 Pg. 131-4 (Feb 2008) ISSN: 1009-3591 [Print] China
• PMID: 18390177 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Adrenergic alpha-Antagonists
• Anti-Bacterial Agents

Topics

• Adrenergic alpha-Antagonists (therapeutic use)
• Adult
• Aged
• Aged, 80 and over
• Anti-Bacterial Agents (therapeutic use)
• Drug Therapy, Combination
• Follow-Up Studies
• Granuloma (diagnosis, diagnostic imaging, drug therapy)
• Humans
• Male
• Middle Aged
• Prostatitis (diagnosis, diagnostic imaging, drug therapy)
• Rectum
• Ultrasonography (methods)