Rapid control of malaria by means of indoor residual spraying of alphacypermethrin in the Democratic Republic of São Tomé and Príncipe.

Abstract

A nationwide yearly cycle of indoor residual spraying (IRS) with a pyrethroid, alphacypermethrin, at a dosage of 50 mg/m(2) was instituted in 2004 in the Democratic Republic of São Tomé and Príncipe. Rates of IRS acceptance were high, varying from 82% to 95% for dwellings and outhouses. Epidemiologic surveys of the children < 9 years of age before and after the first IRS cycle revealed a rapid reduction in malaria. Overall prevalence of malaria parasitemia for all districts was lowered from 20.1% to 2.8% at 12 months after the first IRS and reached 0.7% at 8 months after the second IRS. Longer insecticidal persistence was found on wood than on cement with alphacypermethrin.

• Authors: Lien Fen Tseng, Wen Chun Chang, Maria Conceição Ferreira, Cheng Hua Wu, Herodes Sacramento Rampão, Jih Ching Lien
• Journal: The American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 78 Issue 2 Pg. 248-50 (Feb 2008) ISSN: 0002-9637 [Print] United States
• PMID: 18256424 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Insecticides
• Pyrethrins
• cypermethrin

Topics

• Animals
• Anopheles (parasitology)
• Atlantic Islands (epidemiology)
• Child
• Child, Preschool
• Housing
• Humans
• Insect Vectors (parasitology)
• Insecticides
• Malaria (epidemiology, prevention & control)
• Mosquito Control (methods)
• Parasitemia (epidemiology, prevention & control)
• Plasmodium (isolation & purification)
• Pyrethrins
• Time Factors
• Wood