Antiarrhythmic activity of n-tyrosol during acute myocardial ischemia and reperfusion.

Abstract

Antiarrhythmic activity of n-tyrosol was demonstrated on the model of early occlusion and reperfusion arrhythmia. The preparation reduces the incidence of ventricular tachycardia and fibrillation, increases the percent of animals without ventricular arrhythmia, and moderates the severity of developing ventricular arrhythmias.

• Authors: G A Chernyshova, M B Plotnikov, V I Smol'yakova, I V Golubeva, O I Aliev, T G Tolstikova, A P Krysin, I V Sorokina
• Journal: Bulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 143 Issue 6 Pg. 689-91 (Jun 2007) ISSN: 0007-4888 [Print] United States
• PMID: 18239802 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Arrhythmia Agents
• 4-hydroxyphenylethanol
• Phenylethyl Alcohol

Topics

• Animals
• Anti-Arrhythmia Agents (therapeutic use)
• Myocardial Reperfusion Injury (drug therapy)
• Phenylethyl Alcohol (analogs & derivatives, therapeutic use)
• Rats
• Rats, Wistar
• Tachycardia, Ventricular (prevention & control)
• Ventricular Fibrillation (prevention & control)