[A case of severe summer-type hypersensitivity pneumonitis treated with high-dose administration of steroid].

Abstract

A 40-year-old man who lived in a wooden house built 30 years ago presented with complaints of fever, dry cough and dyspnea. Chest X-ray findings showed interstitial shadows throughout bilateral lung fields. After admission, high-dose administration of 3000 mg of methylprednisolone was performed because of deterioration of chest X-ray shadows and symptoms. In a week, clinical data and symptoms improved. Findings of BAL fluid on admission revealed a relative increase of lymphocytes, neutrophils and mast cells, and pathological findings of transbronchial lung biopsy revealed non-caseous granulation and alveolitis. Precipitating antibodies and indirect fluorescent antibodies against Trichosporon cutaneum and Cryptococcus neoformans had positive reactions and T. cutaneum was isolated and identified from the patient's house. A diagnosis of summer-type hypersensitivity pneumonitis was made according to the criteria advocated by Ando et al. This seemed to be a rare case of summer-type hypersensitivity pneumonitis prolonged after isolation from his normal living environment, successfully treated by high-dose administration of steroid.

• Authors: M Arai, H Kawada, T Kaburagi, N Sakai, Y Kudou, M Kawakami, K Konno, T Takizawa
• Journal: Nihon Kyobu Shikkan Gakkai zasshi (Nihon Kyobu Shikkan Gakkai Zasshi) Vol. 29 Issue 11 Pg. 1457-63 (Nov 1991) ISSN: 0301-1542 [Print] Japan
• PMID: 1770686 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Methylprednisolone

Topics

• Adult
• Alveolitis, Extrinsic Allergic (drug therapy)
• Drug Administration Schedule
• Humans
• Male
• Methylprednisolone (administration & dosage, therapeutic use)
• Seasons