Abstract | OBJECT: METHODS: A prospective observational study of 130 consecutive patients who underwent surgery for reconstruction of the posterior wall of the drilled porus acusticus with HAC was conducted between October 2002 and September 2005. All patients underwent a retrosigmoid transmeatal approach for VS resection and were followed up to document cases of CSF rhinorrhea, incisional CSF leak, meningitis, or rhinorrhea-associated meningitis. A cohort of 150 patients with VSs who were treated with the same surgical approach but without HAC reconstruction served as a control group. RESULTS: The authors found that HAC reconstruction of the porus acusticus wall significantly reduced the rate of postoperative CSF rhinorrhea in their patients. In the patients treated with HAC, rhinorrhea developed in only three patients (2.3%) compared with 18 patients (12%) in the control group. This was a statistically significant finding (p = 0.002, odds ratio = 5.8). CONCLUSIONS: The use of HAC in the reconstruction of the drilled posterior wall of the porus acusticus, occluding exposed air cells, greatly reduces the risk of CSF rhinorrhea.
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Authors | Clinton J Baird, Alia Hdeib, Ian Suk, Howard W Francis, Michael J Holliday, Rafael J Tamargo, Henry Brem, Donlin M Long |
Journal | Journal of neurosurgery
(J Neurosurg)
Vol. 107
Issue 2
Pg. 347-51
(Aug 2007)
ISSN: 0022-3085 [Print] United States |
PMID | 17695389
(Publication Type: Controlled Clinical Trial, Journal Article)
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Chemical References |
- Hydroxyapatites
- hydroxyapatite cement
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Topics |
- Adult
- Cerebrospinal Fluid Rhinorrhea
(etiology, prevention & control)
- Follow-Up Studies
- Humans
- Hydroxyapatites
(therapeutic use)
- Middle Aged
- Neuroma, Acoustic
(pathology, surgery)
- Petrous Bone
(surgery)
- Postoperative Complications
- Prospective Studies
- Treatment Outcome
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